Dental Abnormalities | Ask the Geneticist (SM)

Q&A about disorders characterized by defects in the formation of teeth that are influenced in whole or part by genetic factors. Examples include dentinogenesis imperfecta and amelogenesis imperfecta.

Other information about dental problems:

-Merck Manual

http://www.merck.com/mmhe/sec08.html

Subtopics

Abnormal tooth shape (1) Amelogenesis imperfecta (12) Calculus formation (1) Dentinogenesis Imperfecta (10) Enamel hypoplasia (1) Extra Teeth (Hyperdontia) (1) Miscellaneous/Unclear Diagnosis (3) Missing Teeth (6) No Sub-topic (0) Showing 35 questions

Displaying: All questions - use the list above to filter results.


	Question		Date



	I'm wondering if it's possible that my daughter might have dentinogenisis imperfecta, but in only one quarter of her mouth. Also, can it be that she got it from myself, who (I) have an aunt and 2 cousins with osteogenisis imperfecta. Their cases are mild and each of them have only broken less than 10 bones so far. They do not have dentinogenisis. Could I be a carrier of both? View Answer		2009-10-30


	To what stage of tooth development the amelogenesis imperfecta is linked to? View Answer		2009-10-16


	Both my grandfather and father have congenitally missing permanent teeth. I am not sure if this is also genetic, but their teeth are in very poor condition. My siblings and I do not have this problem. Is this something that we should worry about passing on to our children? View Answer		2009-09-29


	Ameliogenesis imperfecta runs in my husband's family, but only in males (none of the daughters had it or passed it on to their female or male children). Of our 3 sons, 2 were born with AI. Our other son, however, does not have this condition (both baby and adult teeth have come in with normal enamel color and roots). Is it possible for him to still pass it on to his children? View Answer		2009-07-14


	When a child has huge gaps in his teeth & only has 08 teeth As if he has lost some instead of 10 @ the age of four is that a sign of down syndrome? View Answer		2009-04-16


	I have a 19 year old daughter who was diagnosed with Dentinogenisis Imperfecti, I also have a 14 month old son who likely has the same condition as his teeth have come in just as hers did with a bluish tint and a hint of transperancy to them. My husband was diagnosed with Amelogenisis Imperfecta back in the early 70's. His father as well as at least one of his fathers siblings that we know of also had been diagnosed with AI. I can not find much info on my husbands diagnosis, also I am curious if he may have been mis diagnosed or if our children have been mis diagnosed. Is it possible for them to have two different disorders and can I get more info on Amelogenisis Imperfecti? View Answer		2009-02-18


	Hi, I have the amelogenesis imperfecta disorder and my teeth are really bad. I can hardly enjoy any of my meals because my teeth would start to hurt. Getting all my teeth fix would be way too expensive for me (i'm in my early 20's). So my main question is can I claim this as a disability and get help? It is impossible for me to get this fix myself and my teeth is getting worse. I'm in alot of physical pain and also very stress and of course very sad....Please help View Answer		2009-01-14


	I'm a young female with amelogenesis imperfecta ans dentiogenesis imperfecta, and my family has no history for this disease. I want to know the related problems of my condition and the probabilities of inhereted this disease to my child in future. please i need the answer as fast as possable View Answer		2008-11-07


	My 8 year old son has had perfect baby teeth. However, the first year adult molars that have come in are very brown and week. The dentist says it is "Amelogenesis imperfecta" also known as enamel dysplasia. The 6 permanent teeth he has in front is normal. My question is: Will his 2nd & 3rd set of molars come in with " Amelogenesis imperfecta" or will they be normal? What are his chances of his other permanent teeth coming in with this condition? Also, if it does affect all of his molars, what options do we have? We have already had to fix both the right & left side upper 1st molar and we are scheduled to have the bottom left fixed in 3 weeks. Will the teeth that are affeted by this genetic disorder continue to break? View Answer		2008-11-06


	Hi, My 10 month old son recently went for his first dentist appt last week. He has very small, lower central incisors and his top incisors are now coming in. The dnetist told us that they seem abnormal and we should go see a genticist. So we do have appt this week at Boston Childrens Hospital. We are freaking out, worried about Williamsyndrome and other disorders. The thing that is strange is that he is developmentally fine, he is walking, babling, very smart, and he looks normal, none of the blatant features. Any thoughts? By the way, his top teeth appear to be normal size. View Answer		2008-09-22


	Is it possible that there is a connection between myotonia congenita CLCN1and the deterioration of my teeth Ive been told i have no enamel which has caused them to fall apart both baby teeth and now my adult teeth. my children who also show signs of myotonia congenita also are having same problem with teeth. View Answer		2008-08-27


	A relative of mine was told by her dentist that her son has an extra tooth, and that this has been linked to a risk of colon cancer, possibly at a young age. Now she is worrying about this and wondering whether to have the child genetically tested. Isn't this an overreaction? What are the statistical chances for colon cancer even if he were to have the gene? And how many people simply have extra teeth with no link at all to genetic pre-disposition to cancer? Finally, if the risk is very small, should a dentist even mention this to a parent? View Answer		2008-05-07


	Hi, i am a married gal, who is having 8 missing teeth(after the age of 10). Thus, i have put a crown(ceramic tooth) & doctor had informed me that, this is a heriditary disease. Presently, i am worried about my child to be born. I am plannign to get pregnant within 3 months. My husband has got no mising teeth. Is there any way to get my husbands characteristics ONLY to my child or is there anyway to prevent "missing teeth disorder" to pass to my child. Please help me out. I do not want my child to suffer the mental pressure, which i have sufffered in my childhood. View Answer		2008-05-06


	My daughter, age six was diagnosed with Amelogenesis Imperfecta. Our dentist told us to have her tested for a bone disorder. I have searched for additional information to support his statement, but to no avail. We have contacted our family doctor. Can someone provide resources to support the association of Amelogenesis Imperfecta and bone disorders? Thank you. View Answer		2008-04-25


	I have Dentinogenesis imperfecta, as do two of my four children. My mother, grandfather, uncle, and a host of cousins have this condition. My question is this; my daughter, who has the condition, is about to get married, and has concerns about passing on this defective gene to her offspring. Is their any way to prevent this? View Answer		2008-04-07


	I have dentinogenisis imperfecta. I've read some of these stories and they are very similar to mine. I was fortunate enough to be able to be a patient at UOP's school of dentistry in San Fransisco and have protective work done on my teeth beginning when I was around 10. I don't have crowns on all my teeth and my adult teeth have not worn down at all in comparison to how my baby teeth did. Is there a website or way to contact some of these people to let them know what I had done so they can benefit from it too? A way we can let them know what dentists to see or how to point their dentists in the right direction?? View Answer		2008-04-07


	I have Hypomaturation Amelogenesis Imperfecta and I was wandering what are the odds of me passing it onto my children? View Answer		2008-02-26


	I heard that there is a lesser possibility for a child to get affected by the Dentinogenesis defecta from its father than its monther. Please clarify this and tell me what treatments a mother can take before pregnency sothat the child won't get this defect, in the situation of the father is having such a defect, but not mother. Thankyou! View Answer		2008-01-28


	I have an 8 year old daughter w/ no enamel on her permanent teeth on the right side of her mouth. My husband and I have checked with both of our families and neither have any problems with teeth. What are possible causes are there for this condition? View Answer		2008-01-15


	Hello I am a mother of one, I inherited amelogenesis imperfecta (teeth disorder). I have it and my mother has it. my first daughter does not have this disorder,my husband and I are wanting to have another child,but I feel like I got lucky with my first child not getting this disorder. If you could be so kind to tell me the chances of a future child of mine would inherit this disorder. Here is a list of family members that have amelogenesis imperfecta. My grandfather had it; he had 4 daughters and the eldest had it. Then my mother the 3rd daughter had it. My aunt had 3 boys and the middle boy had it. My mother had 2 boys and me the youngest only female and i have it. I cant find a pattern but maybe you the pro. can. Please help me,this means alot for my future. View Answer		2008-01-14


	i was wanting to know if you know why people could be missing their permanent teeth? i am missing 2, one of my kids is missing 4, another 6 and my daughter is missing 8. this is just to crazy. i have never heard such a thing. them plus my oldest also have chairi malformation. and their doc says 4 of my kids are hyper something in their joints. they want to send them to genetic doctor. View Answer		2008-01-13


	My boyfriend was born with ameliogenesis imperfecta and his two children also have the problem. We are talking about having a child and I wanted to know if there is anything I can do to prevent my child from carrying this gene. Is there anyway to remove it from the sperm? View Answer		2007-12-07


	I have dentingenesis imperfecta but the thing is I am already loosing my teeth at age 19. Is there any funding that can help me? My parents are out of the question and i don't have a job that can pay all that money for a partail. what do i do? I am freaking out because i need more teeth pulled but no funding. Just because i have this disease means i have to walk around with no teeth at age 19? View Answer		2007-07-17


	I have a congenital dental/medical problem that seems to be "outside of the box". I am looking for an article or statistics regarding the percentage of the population that have missing teeth, and in particular, the amount of people that were born with no second teeth. I was born without my upper four front teeth and four others, too. I wore a partial plate since I was four years old. Then when the teeth that held the plate starting falling out, I didn't have any to take their place, so the rest of my teeth were pulled and immediate dentures put in. In 2000, I had a tissue reduction (lower) and graft. Now, I am almost 57 years old, my gums are shrinking, and in order to hold my lower dentures in place, I will need a bone graft and implants. Since this is not a personal choice, but a necessity, I would like to have some help with proving to the insurance companies how rare this is, and that it is a medical necessity, not an elective procedure. Thank you. View Answer		2007-07-16


	In a twele year old child,normally no calculus is seen on the teeth,where as in cystic fibrosis calculus is present. Why,what is the mechanism. is there any literature regarding the same. View Answer		2007-06-11


	My grandaughter is two and her teeth have came in. The teeth are the oddest shape we have ever seen. The front teeth look like regular teeth except the whole center of each tooth isn't there, resulting in two points on each tooth. All of her teeth are pointed. They are the strangest shape we have ever seen. She has no problem eating or drinking with them, but they are very odd. What could this be? She is developing normal in all other ways. View Answer		2007-04-30


	i have yellow teeth, i was born was it and it is called (please forgive the spelling) amillio genousis imperfectous. My question is how rare is the disease and is there any real treatment? View Answer		2007-02-23


	We believe our daughter (11 months old, adopted from Guatemala) may have Amelogenesis Imperfecta. Her teeth are very oddly shaped, with ridges at the bottom. How is this condition diagnosed, and what does it mean for her 'dental future'? Will she get cavities more often, or have teeth that are easily broken? View Answer		2006-11-05


	Amelogenesis imperfecta may be a genetic condition in our family (husband's father). My 10 month old daughter has malformed enamel on all 6 of her primary teeth. We must do IVF with ICSI due to severe male factor and female factor infertility. Is there a way to use PGD to test for AI? View Answer		2006-09-08


	I have dentinogenesis imperfecta wich is a autosomal dominant genetic disorder. My mother has it, I have it and my daughter has it. We do not know of anyone before my mother. My son did not get it. Is there a way of preventing this genetic disorder in my future children? (Mutations in the DSPP gene cause dentinogenesis imperfecta.) View Answer		2006-08-21


	I know someone with Dentinogenesis Imperfecta and they seem to be not maturing properly through puberty. He is 17 and has not shown signs of puberty except for spermarche. I am inquiring if this genetic defect could have something to do with these issues or if it is possible to have a related disorder. View Answer		2006-07-03


	I have two boys ages 6 and 2. There is some kind of hereditary problem with the teeth development that runs in my mom's side of the family. It seems to be passed from the mothers to the sons. My boys are both missing teeth. My 6 year old has 15 teeth. He recently had x-rays done and they showed that he only has 6 permanent teeth that will be coming in. My 2 year old has not been to the dentist yet, but is missing teeth also in some of the same spots the 6 year old is. If anyone could give me some info or let me know what i need to do to find out what this disorder is, I would greatly appreciate it. View Answer		2006-06-06


	I have dentinogenesis imperfecta, which runs in my family. When my mom had it as a child, it was an unfamiliar disease. I had lots of dentistry at a practicing dental college in SF, Calif. so I know the disease is fairly new to the research field. I am 44. My mom is 68. We are both having lots of pain. My mom is far worse off than I am...stiffness, severe pain, weakness. We are researching her problems through specialists, but I am wondering, if anywhere down the line that a connection has been made between this dental disease having an impact on bone weakness/pain, etc. Any info would be appreciated. View Answer		2006-03-08


	Hello! I have a daughter who has Dentinogensis Imperfecta. Her father also had this genetic tooth condition as did family members for generations as far back as we can remember. However, back when her father had these bad teeth they just pulled them and fitted him with Dentures. But, as a young child, we chose to do whatever we could to save her natural teeth and fitted her baby molars with stainless steel crowns and then her permanent molars with procelain crowns. However, now that she is an adult (26 years of age) she has had to replace several of her procelain crowns as her teeth under the crowns had deteroited to the point that they had to be redone. She now has had two teeth break, one they had to crown and the other one they had to extract as it broke in half down into the root of the tooth. All this after also putting thousands of dollars over four years of straightening what were also crooked teeth. But now she feels we all have put enough money into what we all feel are pretty ugly teeth with no guarantee that anything else she does for these teeth will last. We all feel like we're just pouring money into something that will never be considered "Good Teeth." But I guess the most frustrating about this whole ordeal to her and us as her parents is the fact that we can and never have been able to even find a Dentist who even knows more about this condition than we do. They all have told us that anything they do is just a guess as to even if it will work or how long any treatment would last. And since this Genetic condition is not listed in your Question Catergories. I am not even sure you'll be able to help us with any information regarding it. But if you can we would greatly appreciate it. View Answer		2006-02-21


	My husband has Dentinogenesis Imperfecta. He and his brother inherited this disease from their mother. It is my understanding that in determining the possibility of our child having this condition, I might as well assume that it will be a coin flop: 50 percent chance. Is this the case? If so, are their any options for genetic therapy? View Answer		2005-09-14

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