Katie Rudd, Ph.D.

Assistant Professor

Office: 5049 Claudia Nance Rollins

Lab: 5043 CNR

Phone: 404-727-9486

Email: krudd@genetics.emory.edu

Additional Contact Information

Mailing Address:

5049 Claudia Nance Rollins

1518 Clifton Road

Atlanta, GA 30322

Additional Websites

Research Interests

Genomic variation is a major source of human diversity and disease. We focus on variation at the chromosome level, investigating the mechanisms of DNA breakage and repair that generate deletions, duplications, translocations, and more complex chromosome rearrangements. We also study the impact of chromosome rearrangements on nearby genes and chromatin environments. Our goal is to unravel the mechanisms and epigenetic effects of human chromosome rearrangements.

Areas of Specialization

  • Subtelomeres
  • Chromosome breakage
  • DNA repair
  • Chromosome biology
  • Genome evolution


  • Fellowship, Medical Genetics, University of Washington, Seattle, WA,2007
  • PhD, Genetics, Case Western Reserve University, Cleveland, OH,2005
  • BS, Biology, The College of William and Mary, Williamsburg, VA,1998

Board Certifications

  • 2007 Clinical Cytogenetics, American Board of Medical Genetics

Honors and Awards

  • 2009: March of Dimes Basil O’Connor Starter Scholar Research Award


Newman, S., Hermetz, K.E., Weckselblatt, B., Rudd M.K. 2015. Next-generation sequencing of duplication CNVs reveals that most are tandem and some create fusion genes at breakpoints. American Journal of Human Genetics. 96(2):208-20.

Hermetz, K.E., Newman, S., Martin, C.L., Ballif, B.C., Shaffer, L.C., Cody, J.D., Rudd, M.K. 2014. Large inverted duplications in the human genome form via a fold-back mechanism. PLoS Genetics, 10(1):e1004139.

Goldlust, I.S., Hermetz, K.E., Catalano, L.M., Barfield, R.T., Cozad, R.A., Wynn, G., Ozdemir, A.C., Conneely, K.N., Mulle, J.G., Dharamrup, S., Hegde, M.R., Kim, K.H., Angle, B., Colley, A., Webb, A.E., Thorland, E.C., Ellison, J., Rosenfeld, J.A., Ballif, B.C., Shaffer, L.G., Demmer, L.A., Unique Rare Chromosome Disorder Support Group, Rudd, M.K. 2013. Mouse model implicates GNB3 duplication in a childhood obesity syndrome. Proceedings of the National Academy of Sciences 110(37):14990-4.

Mason-Suares, H., Kim, W., Grimmett, L., Williams, E.S., Horner, V.L., Kunig, D., Goldlust, I.S., Wu, B., Shen, Y., Miller, D.T., Martin, C.L., Rudd, M.K. 2013. Density matters: comparison of array platforms for detection of copy-number variation and copy-neutral abnormalities. Genetics in Medicine 15(9):706-12.

Hermetz, K.E., Surti, U., Cody, J.D., Rudd, M.K. 2012. A recurrent translocation is mediated by homologous recombination between HERV-H elements. Molecular Cytogenetics 5(1):6.

Luo, Y.,+ Hermetz, K.E.,+ Jackson, J.M., Mulle, J.G., Dodd, A., Tsuchiya, K.D., Ballif, B.C., Shaffer, L.G., Cody, J.D., Ledbetter, D.H., Martin, C.L., Rudd, M.K. 2011. Diverse mutational mechanisms cause pathogenic subtelomeric rearrangements. Human Molecular Genetics 1;20(19):3769-3778.
+These authors contributed equally to this work.

Rudd, M.K., Keene, J., Bunke, B., Kaminsky, E.B., Adam, M., Mulle, J., Ledbetter, D.H., Martin, C.L. 2009. Segmental duplications mediate novel, clinically relevant chromosome rearrangements. Human Molecular Genetics 18(16):2957-2962.

Rudd, M.K., Endicott, R., Friedman, C., Walker, M., Young, J.M., Osoegawa, K., NISC Comparative Sequencing Program, de Jong, P.J., Green, E.D., and Trask, B.J. 2009. Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event. Genome Research 19: 33-41.

Rudd, M.K. 2007. Subtelomeres; evolution in the human genome. In: ENCYCLOPEDIA OF LIFE SCIENCES. John Wiley & Sons, Ltd. Edited by Kehrer-Sawatzki, H., pp. 1-9.

Rudd, M.K., Friedman, C., Parghi, S.S., Linardopoulou, E.V., Hsu, L., and Trask, B.J. 2007. Elevated rates of sister chromatid exchange at chromosome ends. PLoS Genetics 3: 319-323.

Doggett, N.A., Xie, G., Meincke, L.J., Sutherland, R.D., Mundt, M.O., Berbari, N.S., Davy, B.E., Robinson, M.L., Rudd, M.K., Weber, J.L., Stallings, R.L., and Han, C. 2006. A 360 kb interchromosomal duplication of the human HYDIN locus. Genomics 88: 762-771.

Rudd, M.K., Wray, G.A., and Willard, H.F. 2005. The evolutionary dynamics of alpha satellite. Genome Research 16: 88-96.
Rudd, M.K., Mays, R.W., Schwartz, S., and Willard, H.F. 2003. Human artificial chromosomes with alpha satellite-based de novo centromeres show increased frequency of nondisjunction and anaphase lag. Molecular and Cellular Biology 23: 7689-7697.
Schueler, M.G., Higgins, A.W., Rudd, M.K., Gustashaw, K., and Willard, H.F. 2001. Genomic and genetic definition of a functional human centromere. Science 294: 109-115.