Stephanie Sherman, Ph.D.
Additional Contact Information
Whitehead Biomedical Research Buildling
615 Michael St.
Atlanta, GA 30322
Stephanie L. Sherman obtained her Ph.D. in Human Genetics from Indiana University School of Medicine in 1981 and is currently a Professor in the Department of Human Genetics at Emory University in Atlanta, GA. Her training is in the area of genetic epidemiology and she has been involved in coordination of multi-site projects to unravel the genetic architecture of complex traits and to understand potential gene-environment interactions. Currently, she is involved in research to understand the causes and consequences of trisomy 21, or Down syndrome. She is the co-Director of the Down Syndrome Center at Emory University, a center that combines clinical care, clinical trials and research, and education related to Down syndrome. Current research projects include: 1) identifying risk factors associated with chromosome 21 nondisjunction and 2) identifying genes and environmental factors that explain the large variation in severity of Down syndrome-associated conditions, including cognition and behavior. Dr. Sherman’s other research program focuses on the identifying genes that modify the presentation of fragile X-associated disorders, including co-occurring conditions (e.g. seizures) among those with fragile X syndrome, age of onset of fragile X-associated primary ovarian failure (FXPOI) among women with the FMR1 premutation, and age of onset and severity of fragile X-associated tremor/ataxia syndrome (FXTAS) among men with the FMR1 premutation. All projects have the goal to identify perturbed biological pathways for targets of therapeutic interventions. Lastly, Dr. Sherman is involved in training graduate students and post-doctoral fellows in genetic epidemiology.
Areas of Specialization
- Genetic causes of intellectual and developmental disorders
- Nondisjunction of human chromosomes
- Primary ovarian insufficiency
- Genetic mapping of complex traits
- Fragile X syndrome
- Down syndrome
- PhD, Human Genetics, Indiana University Medical School, 1975-1981
- BS, North Carolina State University,
- 1984, Ph.D. Medical Geneticist, American Board of Medical Genetics
- American Society of Human Genetics
- International Genetic Epidemiology Society
- View publications on PubMed