Michael E Zwick, Ph.D.

Associate Professor

Departments of Human Genetics and Pediatrics

Assistant Dean of Research

Emory University School of Medicine

Assistant Vice President for Research

Robert W. Woodruff Health Sciences Center

Office: 331 Whitehead Biomedical Research Building

Lab: 335 Whitehead Biomedical Research Building

Phone: 404-727-9924

Email: mzwick@emory.edu

Additional Contact Information

Mailing Address:

Whitehead Biomedical Research Building

615 Michael St.

Atlanta, GA 30322

Additional Websites

Research Interests

I use cutting-edge genomics technologies to identify rare genetic variation that contributes to common pediatric disorders. My main areas of interest include autism, congenital heart defects in Down syndrome, early-onset Inflammatory Bowel Disease (IBD), and juvenile arthritis. Current projects include:

Identifying Autism Susceptibility Genes: I am a member of the Autism Sequencing Consortium (ASC) and co-lead the membership committee for the ASC.

Copy Number Variation as a Cause of Congenital Heart Defects in Down Syndrome: The genetic causes of congenital heart defects (CHD) remain largely undiscovered. Individuals with trisomy 21, the cause of Down Syndrome, have much higher rates of CHD, including the very severe atrioventricular septal defects (AVSD). Our project aims to identify both structural genetic variation and common single nucleotide polymorphisms that act to increase the risk of AVSD. Identifying the genetic basis of this disorder can provide insights into the origins of CHD and ultimately lead to improved methods of treatment and prevention.This work is funded by both the National Institutes of Health/National Heart, Lung and Blood Institute (http://www.nhlbi.nih.gov/)

Early-onset forms of Inflammatory Bowel Disease (IBD): With collaborators Subra Kugathasan, David Cutler, Mike Epstein.

Software Tools We Have Developed With Collaborators:

SeqAnt - Sequence Annotator (http://seqant.genetics.emory.edu/)

MOPed - Microarray Oligonucleotide Probe Designer (http://moped.genetics.emory.edu/)

My Graduate Programs at Emory

Graduate Program in Population Biology, Ecology and Evolution (PBEE)


Graduate Program in Genetics and Molecular Biology (GMB)


Areas of Specialization

  • Human Disease Gene Mapping
  • Population Biology, Population Genetics, Population Genomics
  • Methods of Targeted Enrichment and Next Generation Sequencing
  • Open Source Software Tools for Genomics


  • Postdoctoral Fellow, Johns Hopkins University School of Medicine, 2000-2002
  • Postdoctoral Fellow, Case Western Reserve University School of Medicine, 1999-2000
  • PhD, University of California at Davis, Davis, CA,1993-1998
  • BS, Cornell University, Ithaca, NY,1985-1989