R01 DA038453 Weinshenker/Paladini (MPI) 04/01/15-01/31/20
Mechanisms of cocaine hypersensitivity following chronic DBH inhibition
The goal of this project is to determine the molecular and cellular underpinnings of behavioral hypersensitivity to cocaine in mice lacking norepinephrine.
RF1 AG047667 Weinshenker (PI) 07/01/14-06/30/19
Consequences of locus coeruleus activation in a rat model of Alzheimer’s disease
The goal of this project is to determine whether activation of the locus coeruleus can ameliorate Alzheimer’s disease-like neuropathology and cognitive deficits in a rat model of Alzheimer’s disease.
R01 GM097331 Weinshenker/Warren/Caspary (MPI) 03/05/12-01/31/17 (in NCE)
Characterization of the Schizophrenia-associated 3q29 Deletion in Mouse
The major goal of this project is to generate and characterize mice bearing a 3q29 deletion that increases the risk of schizophrenia and intellectual disability in humans, and to identify the gene(s) within that interval responsible for the phenotypes.
R21 DA040788 Weinshenker (PI) 07/01/16-06/30/18
Neurobiology of reward choice
The goal of this project to determine whether increasing the salience/value of a natural reward can shift behavior a novel food vs. cocaine choice procedure.
R01 AG033678 Boyle (PI) 08/01/15-04/30/20
Epidemiologic Study of Decision Making in Preclinical Alzheimer’s Disease
The goal of this project is to determine the causes and consequences of age-related changes in decision making over time.
R21 NS098776 Escayg (PI) 05/12/16-05/31/18
Toward the development of an effective treatment for SCN1A derived epilepsy.
The goal of this project is to develop pharmacotherapies in mice for epilepsy caused by sodium channel gene mutations.
P30 NS055077 Levey (PI) 08/01/15-06/30/19
Emory Neuroscience NINDS Core Facilities (ENNCF)
The goal of this project is to maintain and continue support for the Emory Neuroscience NINDS Core Facilities
and provide consolidated resources and expertise to NINDS funded projects as well as projects aligned to the NINDS mission of reducing the burden of neurological diseases.
Role: Scientific Director, Rodent Behavioral Core
IIRG-13-278692 Weinshenker (PI) 09/01/13-08/31/16
Does Alzheimer’s disease pathogenesis begin in the locus coeruleus?
The goal of this project is to assess the neurotoxicity and transmission of aberrant tau in the locus coeruleus.